en گروه سرامیک Ceramic Materials and Engineering Research Paper Research Paper The Nano Hydroxyapatite (HAp), HAp/PEG and HAp/PVP powders derived from both <em>Gastropod</em> shell (natural source) and chemical precursor by the precipitation method were characterized through various characterization techniques such as FT-IR, XRD, SEM-EDX, TEM, Antibacterial activity and SBF analysis. Based on the structural, chemical, morphological and biological characteristics, HAp/PVP from natural and chemical precursors have been compared successfully. Calculated structural parameters, crystallinity index, C/P ratio, morphology, <em>antibacterial activity </em>and SBF analysis <em>of the</em> products show that HAp/PVP-S (derived from a natural source) exhibits good mechanical property, rod like morphology, good <em>antibacterial activity</em> and apatite formation ability at <em>14 days</em>. EDX analysis also shows the presence of carbon and sodium in HAp/PVP-S<em>. Comparative analysis reveals that </em>characteristics of HAp/PVP-S such as high carbonate content, low crystallite size, poor crystalline nature, presence of trace metal, non-stoichiometric elemental composition and rod like crystals which are matched with the characteristics of biological apatite. T<em>hus, the HAp/PVP-S has the ability to form bone apatite.</em> Hydroxyapatite,Precipitation Method,Comparative Analysis,Antibacterial activity,SBF Analysis 91 109 http://ijmse.iust.ac.ir/browse.php?a_code=A-10-3133-1&slc_lang=en&sid=1 Chimmachandiran Suresh Kumar c.sureshkumar1986@gmail.com 1800319475328460011385 1800319475328460011385 No Department of Physics, Thiruvalluvar College of Engineering and Technology, Vandavasi – 604 505, Tamilnadu, India Kaliyan Dhanaraj rajdhana01@gmail.com 1800319475328460011386 1800319475328460011386 No Department of Physics, Arunai Engineering College, Tiruvannamalai – 606 603, Tamilnadu, India Ramasamy Mariappan Vimalathithan vimal.rmv@gmail.com 1800319475328460011387 1800319475328460011387 No Department of Physics, Salem Sowdeswari College (Govt. Aided), Salem – 636 010, Tamilnadu, India Perumal Ilaiyaraja chemila07@gmail.com 1800319475328460011388 1800319475328460011388 No Chemistry Divisions, School of Advanced Sciences, Vellore Institute of Technology Chennai campus, VIT University, Chennai-600127, Tamilnadu, India Govindhasamy Suresh gsureshphy_1983@yahoo.co.in 1800319475328460011389 1800319475328460011389 Yes Department of Physics, Aarupadai Veedu Institute of Technology, Vinayaka Mission’s Research Foundation, Chennai – 603 104, Tamilnadu, India